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驗(yàn)血可預(yù)測(cè)自殺風(fēng)險(xiǎn) 準(zhǔn)確率高達(dá)90%

Blood test can predict risk of suicide

中國(guó)日?qǐng)?bào)網(wǎng) 2014-07-31 16:53

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驗(yàn)血可預(yù)測(cè)自殺風(fēng)險(xiǎn) 準(zhǔn)確率高達(dá)90%
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A blood test that can predict whether someone may attempt suicide has been developed by scientists in a breakthrough which could prevent hundreds of deaths.

American researchers have found that variations in a single gene can be used to predict if someone is likely to take their own life.

Researchers at John Hopkins University, in Baltimore, Maryland, found that the gene SKA2 stopped functioning correctly in people at risk of suicide. The SKA2 gene is found in the prefrontal cortex of the brain, and is involved in preventing negative thoughts and controlling impulsive behaviour.

If there isn't enough SKA2, or it is altered in some way, the body cannot control levels of cortisol. Previous research has shown that people who attempt suicide or who take their own lives have large amounts of cortisol in their systems.

A test could allow doctors or psychologists to place patients on ‘suicide watch’ and restrict their access to drugs or equipment which they could use to end their own life.

The research was reported in the American Journal of Psychology. "We need to study this in a larger sample but we believe that we might be able to monitor the blood to identify those at risk of suicide," Kaminsky said.

"Suicide is a major preventable public health problem, but we have been stymied in our prevention efforts because we have no consistent way to predict those who are at increased risk of killing themselves," says study leader Dr Zachary Kaminsky, an assistant professor of psychiatry and behavioural sciences.

"With a test like ours, we may be able to stem suicide rates by identifying those people and intervening early enough to head off a catastrophe."

The blood test managed to predict those with the most severe risk of suicide with 90 per cent accuracy. They could also spot if someone had already attempted suicide with 96 per cent accuracy, simply by looking at the levels of SKA2.

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據(jù)英國(guó)《每日電訊報(bào)》報(bào)道,研究人員取得科研突破,通過(guò)驗(yàn)血來(lái)預(yù)測(cè)人們是否具有自殺傾向,從而防止眾多悲劇發(fā)生。

美國(guó)研究人員發(fā)現(xiàn),通過(guò)驗(yàn)血可以檢查一種基因是否發(fā)生變異,從而預(yù)測(cè)某人是否企圖自殺。

美國(guó)約翰?霍普金斯大學(xué)研究人員發(fā)現(xiàn),存在自殺風(fēng)險(xiǎn)的人的SKA2基因功能異常。SKA2基因位于大腦前額皮質(zhì),負(fù)責(zé)控制體內(nèi)壓力荷爾蒙皮質(zhì)醇的含量,能夠防止人們產(chǎn)生消極情緒并控制其沖動(dòng)行為。

若體內(nèi)SKA2基因含量不足,或以某種方式發(fā)生變化,人體將無(wú)法有效控制皮質(zhì)醇含量。此前的研究發(fā)現(xiàn),自殺或有自殺傾向的人體內(nèi)皮質(zhì)醇含量較高。

因此,通過(guò)驗(yàn)血檢測(cè)下SKA2的水平或者是否發(fā)生突變,能夠允許醫(yī)生對(duì)具有自殺傾向的人進(jìn)行觀察,同時(shí)防止他們靠近藥品或其它自殺工具。

該研究發(fā)表于《美國(guó)心理學(xué)雜志》,主要負(fù)責(zé)人凱明斯基表示:“該研究還需加大樣本量,但我們相信,可以通過(guò)驗(yàn)血辨認(rèn)出那些具有自殺風(fēng)險(xiǎn)的人?!?/p>

精神病與行為科學(xué)助理教授扎卡里?凱明斯基表示,自殺是我們目前面臨的主要公共健康問(wèn)題,但由于缺乏直觀的途徑預(yù)測(cè)人們的自殺風(fēng)險(xiǎn),導(dǎo)致我們無(wú)法及時(shí)預(yù)防。

“但通過(guò)我們的測(cè)試,我們可以及早確認(rèn)并干預(yù)具有自殺傾向的人群,從而降低社會(huì)自殺率。”

據(jù)報(bào)道,通過(guò)驗(yàn)血預(yù)測(cè)最嚴(yán)重的自殺風(fēng)險(xiǎn)精確度高達(dá)90%,同時(shí),只要簡(jiǎn)單觀測(cè)一下SKA2的水平,便能以96%的精確度判斷某人是否已企圖自殺。

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驗(yàn)血可預(yù)測(cè)自殺風(fēng)險(xiǎn) 準(zhǔn)確率高達(dá)90% 驗(yàn)血可預(yù)測(cè)自殺風(fēng)險(xiǎn) 準(zhǔn)確率高達(dá)90%

(譯者 高晴 編輯 王輝)

 

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